Physiological intracytoplasmic sperm injection (PICSI) is a technique used to select sperm to use in Intracytoplasmic sperm injection (ICSI) treatment. It involves placing sperm with hyaluronic acid (HA), a natural compound found in the body.
Following the PICSI, the injected eggs are incubated overnight and assessed the following morning for evidence of fertilisation. The average fertilisation rate following PICSI is similar to ICSI and IVF, with 60-70% of injected eggs fertilising normally following PICSI.
